SPOT Imaging Solutions -  Digital Microscope Cameras, Microscope Software, Microscope Adapters, Microscope Stands, and Complete Systems for Bioresearch and Clinical Imaging
cameras, microscopes, and macro imaging systems for science and industry

SPOT Imaging Solutions Library
Microscopy and Digital Imaging Articles and White Papers

Here is the SPOT Imaging Solutions online archive of technical articles and white papers on life science imaging topics. If you like these articles, you can subscribe to our newsletter to receive them as they are added.

Subscribe Now >>

When you subscribe, you will be sent an email when new articles are added without having to return to our website to check for changes.

Article Abstract
Improve Patient Outcomes with Video Pathology Consultations: A Literature Review A review of published studies indicates that video conferencing support of intraoperative pathology consultation contributes not only to improved patient outcomes, but also reduces liability and results in significant time savings for the hospital, pathology lab and surgical personnel.
How to Obtain Parfocality Between Camera and Microscope Eyepieces Instructions for configuring your microscope imaging system so that the camera image is in focus at the same time as the image viewed through the microscope eyepieces.
How to Set Koehler Illumination Instructions for setting up a microscope for Koehler illumination to get the best image resolution and contrast.
Magnification and Sample Size Calculations Technical note on how to calculate the magnification and the real size of the specimen on the monitor.
Field of View Calculations Technical note on how to choose the appropriate coupler magnification to obtain a field of view large enough for your specimen on your monitor screen.
Color Space in Microscope Digital Imaging An understanding of color space can help you enhance the quality of your images. In this article we will review three that are commonly used in digital imaging, RGB, HSL and HSV.
Scientific Digital Imaging Key Concepts As fun as taking pictures may be, it is the professional analysis of samples that really counts. This article discusses key concepts of imaging systems and how these concepts contribute to a professional presentation of your work.
The Consumer Digital Camera vs. Scientific Digital Cameras We have all seen the recent improvements in consumer digital cameras. They have gone from low resolution, curiosities to very capable, high resolution, point and shoot cameras. The prices have dropped dramatically making them even more enticing. Do these cameras have a place in pathology?
Got Good Color? When you capture an image of a specimen, you want it to look like what you saw through the eyepieces.  In this article we will cover the basic concepts of color management and what you can do to make sure what you capture is as close to what you see as possible.
3-Shot vs. Color Mosaic This article illustrates the advantages and disadvantages of Color Mosaic and 3-Shot sampling technologies
Image Corrections In this discussion we will explore how variations due to practical hardware considerations are scientifically accounted for and removed, with the goal of providing an image that is the closest match to the specimen.
Image Capture Methods An introduction to 3-shot color image capture with digital cameras
Megapixels per Dollar Consumer marketing has hyped "mega pixels" as the hook on which they hang their hat. In scientific imaging, the number of pixels is only part of the story, in fact, not always the most important part. This article discusses some of the important specifications of pixels and their relationship to real world scientific imaging.
Dynamic Range in Digital Imaging How dynamic range affects the aesthetics of images for documentation, and what effect high dynamic range has on the quantitative imaging process.