SPOT Imaging Solutions brings you powerful but user-friendly software applications for image acquisition, enhancement, and analysis.
Available tools include:
- Exposure settings optimized for different types of microscopy and macroscopy illumination
- Live preview for focusing and framing
- Floating user-defined taskbars
- Time lapse imaging
- Macro scripting
- Peripheral device control
- Measurements
- Cell counting
- Extended depth of focus function
- Deconvolution
- Reporting
- Database archiving
The software is available in different packages so that you pay for only the tools you need, and you can add new features as your experiments change.
All software comes with user manuals, online help, and outstanding phone and web support from our product support specialists.

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Description - Select by
Specification - Select by
Application
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The SPOT Advanced Plus is optimal for low light level fluorescence imaging. Photobleaching can be minimized with image display auto-scaling during live preview and image capture. The Extended Focus algorithm creates a single, fully focused image from a set of images captured through a thick specimen. The SPOT Advanced Plus enables users to time shutters and filter wheels with SPOT camera acquisition, producing an automated imaging system. |
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Using the SPOT Advanced software, images can be archived into a customizable database and repetitive tasks can be simplified with macros and the user-defined floating Easy Essentials™ taskbars. Microscopists capturing fluorescence images with their SPOT camera can merge and palettize images to easily differentiate fluorophores. This is the best software selection for brightfield and fluorescence microscopy. |
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The SPOT Basic application enables microscopists using SPOT cameras to create publication-quality pictures easily. It provides custom reports, dimensional measurements, calibration mark addition, live image previewing, and automatic white balance features that are useful for documenting your work. |
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MetaMorph is designed for demanding quantitative needs in research applications. Its toolbox includes cell counting, deconvolution, image stitching, ratio and calcium imaging, FRET/FRAP, and multi-dimensional imaging. MetaMorph controls SPOT cameras through a custom driver and can also control other manufacturer's cameras and peripherals. |
SPOT Basic
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SPOT Advanced |
SPOT Advanced Plus
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MetaMorph |
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| Full Screen Live Image Preview | √ |
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| Image Annotations Including Lines, Arrows, Circles, Shapes, Pictures, Text | √ |
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| Exportable Measurements Including Area, Perimeter, Length, Angle and Diameter | √ |
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| Time Lapse Imaging | √ |
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| Automatic White Balance | √ |
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| Custom and Preconfigured Color Palettes for Coloring Monochrome Images | √ |
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| Menu-driven Macro Scripting | √ |
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| User-defined Floating Taskbars | √ |
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| Exportable Database | √ |
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Automatic Background Subtraction | √ |
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| Peripheral Device Control | √ |
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| Extended Depth of Focus | √ |
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| Intensity Display Scaling | √ |
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| Cell Counting with Thresholding | √
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| Image Stitching | √
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| Deconvolution | √
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| Brightness Measurements | √
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| FISH/FRAP/FRET and Colocalization Studies | √
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| System Requirements | |||||||||||
PC or Mac |
PC or Mac |
PC or Mac |
PC only
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| Price | |||||||||||
included with SPOT camera purchase or $149 for updates |
$499 |
$999 |
starts at $2300 for offline version without acquisition module
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Key: *: Best Choice for Application √: Capable +: Capability Surpasses Application x: Not Recommended |
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SPOT Basic
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SPOT Advanced |
SPOT Advanced Plus
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MetaMorph |
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Documentation |
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+ |
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Routine Fluorescence |
x |
* |
+ |
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Extreme Low Light Fluorescence |
x |
x |
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* |
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Analysis |
x |
x |
x |
* |
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